Study of the Month, May 2025: Vitamin D & K2 in Implantology – Importance for Bone and Healing

Introduction

Welcome to the "Study of the Month." This article focuses on the roles of vitamins D and K2 in bone health and their significance in biological dentistry. Both vitamins work synergistically and play crucial roles in successful bone regeneration.

Objectives 

The study aimed to: 

• Ensure adequate vitamin D levels (optimal: 40–80 ng/mL) 
• Support calcium absorption and incorporation into the bone matrix 
• Prevent calcium deposits in vessels and organs through vitamin K2 
• Follow a supplementation ratio of 100 mcg K2 per 1,000 IU D3 for balanced intake

Vitamin D3

• Enhances calcium absorption and bone health
• Supports immune function and reduces inflammation
• Target blood level: 40–80 ng/mL
• Supplementation guidance: <40 ng/mL → 10,000 IU/day; 40–80 ng/mL → 5,000 IU/day; >80 ng/mL → 1,000 IU/day

Vitamin K2 

• Activates osteocalcin and Matrix Gla Protein (MGP)
• Directs calcium into bones and prevents vascular deposits
• Recommended: 100 mcg K2 per 1,000 IU D3

Synergy and Benefits

• D3 + K2 increase bone mineral density
• Reduce levels of undercarboxylated osteocalcin
• Protect cardiovascular health

Conclusion

Vitamin D3 enhances calcium absorption, while vitamin K2 directs calcium specifically into the bones. Only together do they exert their full effect: promoting bone stability while simultaneously preventing vascular calcification, a key factor for long-term treatment success. 

Reference

A full report on vitamin D and K2 supplementation can be found in the Swiss Biohealth Clinic (SBC) presentation for the Study of the Month, May 2025.  

Prof. Dr. med. dent. E. Schnurr (Scientific Advisor, SDS)

Provides scientific guidance for SWISS DENTAL SOLUTIONS. She researches the oral microbiome, biofilm infections, and their impact on overall health: from clinical research and data analysis to drug development.

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